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Piperazinum

6XPiper-az
Piperazinum · Piperazine (Uric Acid Solvent) · "The Uric Acid Solvent Compound"
OtherRarePsoricClarke only

Exclusively Documented in Clarke

This remedy is documented exclusively in Clarke's Dictionary of Practical Materia Medica. It does not appear in other classical references in this encyclopedia.

🎯 Acts primarily on uric acid metabolism and renal function, with secondary effects on the nervous system and eyes.
📖 Clarke writes:
Piperazine. Piperazidine. Ethylenimine. Diethylene-diamine. C4H10N2. Trituration. Solution.
👤 Characteristics
Sphere of Action & Core States
Synthetic product, originally intended to replace Spermin (C2H5N), named Dispermine
Differs from Spermin in both chemical and physiological properties
Readily unites with uric acid, forming a very soluble compound (urate of piperazine)
Not entirely oxidized when taken by mouth; part is discoverable unchanged in the urine
Increases the amount of urea in the urine
Dissolves uric acid calculus in normal urine at body temperature
Converts undissolved portions of uric acid calculus to a granular and pulpy condition
Physical Profile & Chemical Properties
Occurs in well-defined, colourless, acicular crystals
Occurs in lustrous tables
Deliquescent
Mostly soluble in water
Key Characteristics & Guiding Symptoms
Used with success in mental diseases
Used with success in lead paralysis with very remarkable results
Used with success in renal colic
Used with success in glaucoma
Acute gout attack, unexpected, following a teaspoonful dose of an effervescing preparation of Piperaz. (Cooper)
Key Symptoms — Give When You See
Dissolves uric acid calculi in the kidneys.
Clarke
Effective in the treatment of renal colic.
Clarke
Clears up symptoms of glaucoma.
Clarke
Used with success in cases of lead paralysis.
Clarke
Increases the amount of urea in the urine.
Clarke
May trigger an unexpected acute attack of gout.
Clarke
Used in the treatment of various mental diseases.
Clarke
Partially excreted unchanged in the urine.
Clarke
📋 Clinical Indications

Conditions Clarke associates with this remedy — no detailed symptom-by-system breakdown exists for this entry.

GlaucomaGoutLead paralysisRenal colic
Open in Clarke
🔑 Modalities
Clarke Exclusive
Worse from
Ingestion of effervescing preparation
acute gout
📚 Sources & References
Clarke's DictionaryBoericke's Materia MedicaHering's Guiding SymptomsHahnemann's Materia Medica PuraKent's Materia MedicaAllen's EncyclopediaPhatak's Concise MM

Compiled from classical homeopathic texts in the public domain. Click any active source badge to open the original text. For educational and reference purposes only. Always consult a qualified homeopath for treatment.